Bio Complete 3 Review: A Unique Probiotic for Gut Health (2024)

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  • Key Takeaways (TL;DR)
  • Bio Complete 3 at a Glance
  • The Cost
  • The Research
  • Safety Considerations
  • Alternatives

Key Takeaways (TL;DR)

  • Bio Complete 3 contains probiotics, prebiotics, and postbiotics, making it a fairly unique probiotic supplement.
  • Its ingredients have a good amount of scientific evidence (especially Baccillus Coagulans) showing their benefit in improving gut health and supporting energy levels.
  • Although this product may promote weight management, it should not be considered a solution for that goal.
  • The ingredients in this product are generally considered safe for healthy people. (See safety section for exceptions.)
  • Bio Complete 3 may be an excellent option for your daily regimen if you find yourself struggling to eat a balanced diet and need support managing a healthy gut.
  • To see results, it is best to take this product consistently. Evidence suggests that taking your probiotic for at least a few months will yield the most benefits, as it takes some time for the healthy bacteria to build up in your body.
  • If you’re unsatisfied, you can return Bio Complete 3 for a refund through the company’s 90-day money-back guarantee.

What Bio Complete 3 Gets Right

  • Offers probiotics, prebiotics, and postbiotics in one supplement.
  • The supplement contains ingredients that have been clinically studied and shown to be effective in improving gut health.
  • Has a 90-day money-back guarantee, even on opened products.

Important Considerations

  • The brand does not list probiotic CFUs per serving, making it impossible to know if the product contains an effective dose.
  • Other key ingredients have promising benefits but are in smaller amounts than what was studied, so they may be underdosed.
  • You must use this product consistently to see results, so consider the ongoing monthly costs.
  • Bio Complete 3 is more expensive than its competitors. But if using the subscription service and buying in bulk, the cost is similar to alternative products.
  • Having to take four capsules a day may not be appealing to some.

Bio Complete 3 at a Glance

Bio Complete 3 from GundryMD is a probiotic supplement created by Dr. Steven Gundry, a cardiac surgeon with over 30 years of experience. It is uniquely designed to support gut health by providing a blend of research-backed probiotics, prebiotics, and postbiotics.

One of the keys to optimal health lives in our gut. Research shows that the microbes living in our intestines interact significantly with our mind, heart, and overall wellness. Ensuring optimal gut health is essential for anyone wanting to take steps towards improving their overall health.

Bio Complete 3 aims to promote total body wellness by offering a comprehensive product to improve your gut health.

How to Take It

The recommended dosage for Bio Complete 3 is two capsules twice per day, taken before meals. For optimal benefits, it is recommended to take this product daily.

Tip: Combine Bio Complete 3 with a well-balanced diet and healthy lifestyle. Include plenty of fiber-rich foods such as whole grains, fruits, and vegetables. Add probiotic-containing foods such as kefir, Greek yogurt, and fermented vegetables to help maintain optimal gut health.

Click to View Supplement Facts

Bio Complete 3’s nutrition information per serving (4 capsules) includes:

  • Calories: 10
  • Total Fat: 1 gram
  • Saturated: 1 gram
  • CoreBiome (Standardized to 30% Tributyrin): 1000 mg
  • SunFiber™: 200 mg
  • ProDURA (Baccillus Coagulans): 16 mg

Other ingredients include Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Sunflower Oil, Fatty Acids Esterfied with Glycerol, Magnesium Stearate, Silica, Maltodextrin.

The Cost Is Not Cheap

Bio Complete 3 is not sold in stores and must be purchased directly online from the Gundry MD brand.

One-Time Purchase

Subscription

1 Bottle (30-day supply)

$69.95

$49.95

3 Bottles (90-day supply)

$188.85 ($62.95 per bottle)

$134.85 ($44.95 per bottle)

6 Bottles (180-day supply)

$353.70 ($58.95 per bottle)

$254.85 ($42.48 per bottle)

Supplements containing prebiotics, probiotics, and postbiotics are typically more expensive than products that only offer probiotics. Still, the one-time purchase price of Bio Complete 3 is more expensive than its competitors. However, buying it through a subscription makes a meaningful difference and makes the price comparable to alternatives.

The brand offers a friendly 90-day money-back guarantee, including for opened products. If you are not fully satisfied with your purchase, you may request a refund minus the shipping cost.

Try Bio Complete 3

Research Behind the Benefits of Bio Complete 3

Although Bio Complete 3 has not been tested as a whole, the supplement contains probiotics, prebiotics, and postbiotics that may help support your gut health and overall wellness. However, it’s important to remember that while certain ingredients produced some early promising results, they are used in smaller amounts in this supplement.

Additionally, the brand does not disclose how many CFUs are available per serving for Bacillus coagulans, which would be helpful considering there is solid research behind this probiotic strain.

Note: CFU stands for Colony Forming Units, representing the number of live and active microorganisms in one serving of a probiotic supplement.

Below we’ll break down the research behind ingredients and their possible roles in providing potential benefits.

Gut Health

Probiotic supplementation in healthy adults may improve the concentration of beneficial gut bacteria, leading to improved digestion, better bowel movements, and less gas and bloating.(1)

Research has found that the probiotic bacillus coagulans can withstand the stomach’s acidic environment to reach the intestine where it grows. Once B. coagulans is active in the small intestine, it will improve the groups of beneficial bacteria, resulting in better digestion, less abdominal pain, and less bloat.(2)

Bio Complete 3 also includes SunFiber, a prebiotic that positively affects digestive health and promotes better stool frequency and consistency. However, studies show that while it is promising, the amount of SunFiber in this supplement is significantly smaller than what was researched.(3)

Energy Support

Studies show that healthy bacteria in the gut are correlated with improved energy. Specifically, the probiotic B. coagulans used in Bio Complete 3 has been shown to aid in the digestion of carbohydrates and protein, allowing the body to utilize nutrients better, which may lead to improved energy.(4, 5)

Food Cravings

Studies have shown that having a positive balance of gut bacteria may lead to fewer cravings and food addictions.(6, 7)

Specifically, SunFiber™ is a soluble dietary fiber made from hydrolyzed guar gum that provides a feeling of fullness, possibly reducing cravings. However, the amount in Bio Complete 3 appears smaller than what was studied.(8)

Weight Management

Research has shown B. coagulans may play a role in the digestion of carbohydrates and protein, maximizing the benefits of protein supplementation. Optimal protein intake and absorption are necessary for weight loss.(5, 9)

Additionally, as mentioned earlier, SubFiber, a soluble fiber, may increase feelings of fullness by improving the good bacteria in your gut and overall digestion, resulting in healthy weight support.(7)

Finally, this supplement also contains Tributyrin, which studies show may play a small role in improving fat metabolism. However, more human research is needed as some studies have been done on animals.(10, 11)

Bio Complete 3 Review: A Unique Probiotic for Gut Health (1)

Consider Safety Before Taking This Supplement

Probiotics such as Bio Complete 3 are generally safe for healthy adults.

While not widely reported, some people may deal with mild side effects from most probiotic supplements, such as diarrhea and bloat, especially when you first start taking them.

However, caution should be used with taking probiotics if:

  • You have a weakened immune system, a critical illness, or have recently had surgery. This is due to a possible risk of infection in certain people.(12, 13)
  • You suffer from GI conditions. Before beginning supplementation, you should review with your physician, as some probiotics may worsen your condition.
  • You are pregnant or nursing. Bio Complete 3 is not intended for pregnant or nursing individuals without doctor supervision.

Bio Complete 3 is gluten-free, vegetarian, and free of added sugars. It has also been third-party tested to ensure purity and potency.

How Bio Complete 3 Compares to Alternatives

Bio Complete 3 is unique by containing prebiotics, probiotics, and postbiotics in its formula. Not many brands offer this combination of ingredients.

The more common ones are synbiotics, which refer to products that contain both prebiotics and probiotics. Seed Daily Synbiotic and Ritual Synbiotic+ are the two best brands we evaluated. Here’s how Bio Complete 3 compares to them.

Bio Complete 3

Seed Daily Synbiotic

Ritual Synbiotic+

3-in-1 (prebiotic, probiotic, and postbiotic)

Probiotic Strains

1

24

2

Clinical Studies

Third-Party Tested

Form & Daily Dosage

4 Capsules

2 Capsules

1 Capsule

Vegan

Subscription Price (30-day supply)

$49.95

$49.99

$54.00

Money-Back Guarantee

90 days

30 days

30 days

Expand to See How This Supplement Compares to These Brands

Vs. Seed Daily Synbiotic

If you are looking for a comprehensive probiotic supplement, Seed Daily Synbiotic is a solid choice.

It contains a blend of 24 clinically-studied probiotic strains and a prebiotic and has been shown to support the following:

  • Digestive health
  • Skin health
  • Nutrient synthesis
  • Heart health

Compared to Bio Complete 3, Seed clearly discloses the probiotic amounts, has undergone more thorough testing, and includes a broader range of probiotic strains for additional health benefits. However, Seed does not contain postbiotics.

Unlike Bio Complete 3, Seed also has a “capsule within a capsule” design to ensure the probiotics are alive when they arrive in your large intestine, so they’re most effective.

Read Our Full Seed Review

Vs. Ritual Synbiotic+

Just like Bio Complete 3, Ritual Synbiotic+ provides a blend of probiotics, prebiotics, and postbiotics to support gut health similarly.

It includes two strains of probiotics with amounts disclosed and has clinical trials to support their benefits.

Ritual also offers a delayed-release capsule to ensure the probiotics reach your intestines, which Bio Complete 3 lacks.

Read Our Full Ritual Synbiotic+ Review

Bio Complete 3 Review: A Unique Probiotic for Gut Health (2)

Try Bio Complete 3

Bio Complete 3 is a unique probiotic supplement that’s backed by research to promote digestive health. It’s also backed by a 90-day money-back guarantee for extra peace of mind.

Bio Complete 3 Review: A Unique Probiotic for Gut Health (2024)

FAQs

Bio Complete 3 Review: A Unique Probiotic for Gut Health? ›

I like this formula of having a prebiotic, probiotic and postbiotic (butyrate). There is no smell and i tolerated it perfectly. I felt that my digestion was better and i felt less hunger. It is expensive but i believe the tradeoff is the higher quality.

What are the side effects of taking Bio Complete 3? ›

Some common side effects you may experience with Bio Complete 3 or any probiotic or fiber supplement include:
  • Passing gas more often.
  • Bloating.
  • Indigestion or mildly upset stomach.
  • Loose stool.
Jan 2, 2024

Is Bio Complete 3 FDA approved? ›

Bio Complete 3 Ingredients and Labeling

The main ingredients include Tributyrin, Sunfiber®, Bacillus coagulans, and flaxseed. These ingredients are generally recognized as safe (GRAS) by the FDA. Bio Complete 3's labeling adheres to FDA guidelines, providing clear dosage instructions and warnings.

What does Bio Complete 3 do for the body? ›

Many users in Bio Complete 3 reviews praise the supplement for better digestive health, less bloating, less gas, reduced unhealthy cravings, weight loss, and boosting energy levels.

What is comparable to Bio Complete 3? ›

Bio Complete 3 and Total Restore are Dr. Gundry's top two best selling supplements for gastrointestinal health. They have entirely different ingredient profiles and are designed to provide support for different health issues–but there is some overlap.

Why do cardiologists warn against probiotics? ›

But, when it comes to pre-and probiotics, cardiologists are warning they aren't a treatment for elevated blood pressure, cholesterol, or other heart health markers. The health benefits of probiotics are also strain-specific, so taking any probiotic off the shelf won't guarantee results.

Who should not take probiotics? ›

However, probiotics are not recommended for use in just a few serious medical conditions, which are listed below:
  • For those who are severely immunosuppressed. ...
  • For those who have pancreatitis. ...
  • For patients who are in the ICU. ...
  • For those that have melaena (dark blood in their faeces)
  • For those with a central venous catheter.

How long does it take for Bio 3 to work? ›

According to Dr. Gundry, you can expect results from Bio Complete 3 within days.

What medications interact with probiotics? ›

Some medications that may interact with certain probiotics include: antibiotics, antifungals (such as clotrimazole, ketoconazole, griseofulvin, nystatin).

Should Bio Complete 3 be taken on an empty stomach? ›

A: The recommended dosage of Bio Complete 3 is two capsules daily, ideally before a meal. Each bottle contains 60 capsules, a one-month supply. For best results, you'll want to be consistent in taking this fast-absorbing formula.

What is a leaky gut? ›

A “leaky gut” is another name for increased intestinal permeability. This is a recognized condition in which the gaps between the cells of your gut lining get bigger. The lining of a healthy gut is semipermeable. It lets through water and nutrients from what you eat and drink.

What are the side effects of Bio 3? ›

Now I know why. It has methyl cellulous [also used in eye drops] which causes bloating, microcrystalline [which causes gas, bloating, depression, forgetfulness, lack of energy, and headaches], and maltodextrin [which is a sugar substitute that has tons of articles debating whether it's safe or not].

What is the best gut repair? ›

Top Gut Healing Supplements Used By Integrative Medicine...
  • L-Glutamine. L-glutamine is the body's most commonly used amino acid (AA) and is used in more metabolic processes than any other AA. ...
  • Zinc Carnosine. ...
  • Digestive Enzymes. ...
  • Probiotics. ...
  • Prebiotics. ...
  • Deglycyrrhizinated licorice root. ...
  • Marshmallow Root. ...
  • Aloe.
Feb 21, 2023

Which probiotic is best for a leaky gut? ›

Some of the most well-researched probiotic strains for gut health include:
  • Lactobacillus plantarum: Found to strengthen the intestinal barrier, reducing gut permeability.
  • Bifidobacterium lactis: Shown to enhance immune function and may help reduce inflammation in the gut.

Do probiotics have side effects on the heart? ›

Damaged heart valves: Some probiotics have caused infections of the inner lining of the heart chambers and heart valve. This is extremely rare, but people with damaged heart valves should stop taking probiotics like Lactobacillus acidophilus before dental procedures or surgical procedures.

Are there any side effects to taking probiotics? ›

Temporary digestive issues like gas and bloating are the most common side effects. If you have these, they tend to subside in a few weeks. To avoid any discomfort, it's a good idea to add probiotics to your diet gradually.

What are the side effects of complete? ›

Constipation, diarrhea, or upset stomach may occur.

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