Bio Complete 3 Review - Must Read This Before Buying (2024)

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About Bio Complete 3

Gundry MD is a health company designed to improve your health and wellness through diet and nutrition.

With a diverse product portfolio that includes supplements, skin care products, functional foods, and even pet food, this company has a lot to offer. One of their flagship products is Bio Complete 3, a supplement designed to optimize your gut health.

Founded by world-renowned cardiac surgeon Dr. Steven Gundry, this company has a ton of followers already, with 142k on Instagram and 83.4k on YouTube. Bio Complete 3 itself has earned hundreds of reviews on its website with a high average rating, so this seems promising.

In this Bio Complete 3 review, I will closely examine the brand and the science behind it to arm you with the tools to make a smart purchase.

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Overview of Bio Complete 3

Bio Complete 3 is one of many wellness products created by Gundry MD. The company’s founder Dr. Gundry is an author and former cardiac surgeon who created his own line of dietary supplements after drawing inspiration from one of his patients.

This patient was overweight, chronically ill, and considered a “hopeless case” by Dr. Gundry’s peers. To his discovery, the patient had reversed his symptoms using a combination of all-natural nutrients. This led the doctor to conduct research, where he learned about the critical importance of gut health for overall health and wellbeing.

Ironically, ‌Dr Gundry was also overweight and out of shape‌. Decades spent treating patients and saving lives had led him to neglect his own health. Meeting this “hopeless” patient and confronting his own personal health led to an epiphany for Dr. Gundry. He would leave his position as a surgeon and chart a new path.

Dr. Gundry would go on to create the Center for Restorative Medicine in California, where he would continue his research on the gut microbiome and eventually create Gundry MD supplements, including Bio Complete 3. Gundry MD products are manufactured in the USA at a Good Manufacturing Practices facility.

Here are some highlights of this probiotic-based formula:


  • Doctor-formulated
  • Strong scientific evidence on key ingredients
  • Fully transparent formula
  • Supports gut health using a multi-faceted approach
  • Many positive customer reviews
  • Free shipping on orders over $60
  • Significant savings for multiple purchases
  • Big discounts and exclusive offers for VIP Members

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Bio Complete 3 Review

Gundry MD is built on the foundation that our health stems from our diet and nutrition. So, Bio Complete 3 is a product formulated to replicate that foundation. Using a mix of prebiotics, probiotics, and butyrate, they made this supplement to target and improve your gut.

Bio Complete 3 is said to improve digestion, reduce food cravings, improve strength, and ultimately help you lose weight faster. This is all thanks to a high number of bacteria they will introduce to your gut to get it working to the best of its ability.

You can purchase a 120-capsule bottle of this natural digestive supplement for $70.

Now, Gundry MD seems to be promising a lot for the price of this product. However, there is a lot of research to back up their claims of this product’s effectiveness in working against indigestion and general gut discomfort.

Now that you have a better idea of why Bio Complete 3 was created, let’s get into how it works.

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Who Is Bio Complete 3 For?

Readers of this Bio Complete 3 review who are experiencing digestive issues, frequent colds or viral infections, a lack of energy, or are having trouble losing weight might be ideal candidates for using this product. These symptoms may show poor gut health, which prebiotics and probiotics can improve.

Healthy adults who are looking to optimize their gut health and improve immune function can use Bio Complete 3. Let’s learn more about these benefits below.

What Are the Benefits of Bio Complete 3?

By optimizing gut health and immune function, the makers of Bio Complete 3 claim users can experience the following benefits:

  • Improved digestion
  • Improved body composition and faster weight loss
  • Reduction in food cravings
  • Improved muscle strength
  • Greater energy and vitality
  • More consistent and easier visits to the bathroom

Let’s learn more about how the ingredients work next in this Bio Complete 3 review.

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How Does Bio Complete 3 Work?

​​Bio Complete 3 works by helping to populate your gut with billions of healthy bacteria. These bacteria are critical to support the health of your immune system.

In fact, it is said that over 70% of your immune system lives in your gut, which is why it is so important to improve your gut health. Gut health equals good overall health!

Using a combination of prebiotics to provide fuel for healthy bacteria, probiotics ensure you have enough healthy bacteria in your gut and butyrate to bulletproof the lining of your gut.

Prebiotics are important for probiotics to function at their best in your body. According to this research study, prebiotics are fermented ingredients that help the bacteria in your gut, boosting your gut health and overall wellbeing.

Another research paper published in The Journal of Nutrition states that prebiotics are so important that may reduce the inflammation in your GI tract, and help with diarrhea, irritable bowel syndrome, ulcerative colitis, and more.

Probiotics are live microorganisms that are used in foods, beverages, or taken in supplement form. Research has shown that they are beneficial for intestinal health and may reduce the risk of various diseases.

Some researchers believe ‌probiotics improve gut health by stimulating the immune system. A study conducted in 2010 showed that a probiotic formula stimulated the immune system. These researchers believe that a deficiency in the immune system can contribute to conditions such as IBS.

While probiotics have all of these great health benefits, current research does not support claims that probiotics help with weight loss.

Next up, let’s dive into the science behind the ingredients in this Bio Complete 3 review.

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What Are the Ingredients In Bio Complete 3?

Bio Complete 3 promotes gut health using a combination of prebiotics, probiotics, and butyrate. Let’s learn more about the science behind the three key Bio Complete 3 ingredients:

CoreBiome (1,000mg)

​​CoreBiome is a patented ingredient ‌in the Bio Complete 3 formula. CoreBiome is standardized for the active ingredient tributyrin.

A study conducted on mice fed a high-fat diet who were given tributyrin found it protected the mice from obesity and insulin resistance. Chronic insulin resistance over time can lead to diabetes.

Sunfiber (200mg)

Sunfiber is another key ingredient in the Bio Complete 3 formula. ​​Sunfiber is a dietary fiber that is made from guar gum. It’s used in a variety of foods, drinks, and supplements.

Scientists investigating the addition of Sunfiber to a soy-based product noted ‌it is an excellent dietary fiber that has been shown to help with digestive issues like diarrhea and constipation. It will help keep your gut bacteria balanced and healthy.

ProDura (16mg)

The third and final key ingredient in Bio Complete 3 is a patented form of bacillus coagulans, which is a probiotic with multiple health benefits.

Bacillus coagulans have been shown to improve digestion, prevent the growth of bad bacteria, and improve immune function.

Based on the many positive effects of bacillus coagulans, scientists hope ‌they will use this probiotic as a therapy for various diseases.

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How to Take Bio Complete 3 and Dosage

Dr. Gundry recommends taking two capsules of Bio Complete 3 twice daily, before meals. You have the option of taking the product with whichever meals you want.

According to Dr. Gundry, consistent use is important to get the most out of the product.

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Bio Complete 3 Side Effects

Readers of this Bio Complete 3 review will be pleased to know that the key ingredients are well researched and safe when used as directed on the label.

Bio Complete 3 side effects can occur if you take too much of the product. For example, probiotics can cause bloating, gas, and diarrhea.

Also, while fiber can be very beneficial for gut health, too much fiber can cause similar side effects as overdoing probiotics.

Studies and toxicological experiments conducted on bacillus coagulans have shown that it is safe. If you have any concerns after reading this Bio Complete 3 review, please consult a healthcare professional with a background in nutrition.

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Bio Complete 3 Reviews: What Do Customers Think?

This supplement has received a ton of positive feedback from many happy customers. Here’s a quick summary of reviews for Bio Complete 3 and Gundry MD:

  • Gundry MD: 4.83/5 following 399 reviews
  • Better Business Bureau: 4.32/5 stars over 3,188 reviews
  • Trustpilot: 4.3/5 stars after 5,428 reviews

One customer wrote: “This supplement has definitely increased the frequency and quantity of bowel movements. I think I am eating less and yet going to the bathroom more! There are way fewer cravings for sweets or other junk food. So far, so good.”

Another customer wrote about the energy boost they felt: “After a few days of using Bio Complete 3 I noticed that I wasn’t so tired after a meal. It had gotten so bad that I usually avoided driving after eating for fear of falling asleep. Now I can eat a full meal and still be wide awake and active. I love this product.”

Feeling lighter seems to be a common result of taking Bio Complete 3 for many customers, not just in the energy department. When it comes to bowel movements, one excited reviewer wrote:

Have suffered from chronic constipation my whole life! I can go as long as a week without a bowel movement. I have used every available remedy on the market with no consistent relief. Without going into further detail of my GI history all I can say is by day 3 of taking Bio Complete 3 I have had a NORMAL bowel movement every morning!!”

Another formerly backed up customer said: “I definitely have less bloating and my bowels are more regular with no constipation. I feel more energetic and a lot less sluggish. I’ve shared my bottles with 3 others and am hopeful bio complete 3 will do wonders for them too.”

This Bio Complete 3 review would be incomplete without reviewing feedback from the Better Business Bureau. Gundry MD has an impressive amount of positive reviews as well. They also have an excellent A+ rating and accreditation by the BBB.

On Trustpilot, the glowing reviews continue. Gundry MD has a high average rating, with 81% of the reviews rated as “great” or “excellent.” Customer reviews are a huge strength for Gundy MD and Bio Complete 3, and speak volumes about the product’s efficacy.

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Is Bio Complete 3 Worth It?

After thoroughly reviewing the scientific evidence on key ingredients, hundreds of customer reviews, testimonials, and feedback about Bio Complete 3, this product is highly recommended.

Dr. Gundry has formulated a first-class, transparent product. While claims about weight loss are lacking in evidence, this supplement looks great for gut health.

Readers of this Bio Complete 3 review who are keen to enhance their digestive health and support immune function should add this brand to their short list.

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Bio Complete 3 Promotions & Discounts

By signing up for a free Gundry MD VIP Wellness Account, you can get Bio Complete 3 for $50, which is a major savings of $20.

You can also save if you buy this product in bulk:

  • 3 bottles: $189 or $135 with a VIP account
  • 6 bottles: $354 or $255 with a VIP account

Even if you don’t decide to become a VIP member, first-time buyers of Bio Complete 3 can experience the same savings. All you need to do is create a free account. And if you follow their Instagram, you can save even more!

Enter the offer code SOCIAL20 to save 20% on all products. This applies to regularly priced products only.

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Where to Buy Bio Complete 3

Bio Complete 3 is only available at the Gundry MD store. They’re not sold in retail stores or on any large ecommerce sites. In fact, Gundry MD has made it clear that any product found on Amazon is counterfeit, so do not buy them.

The official website accepts most major credit cards including Visa, Mastercard, and American Express on their secure payment platform. Customers also have the option of using PayPal to purchase the product. Shipping is free for all US orders over $60.


How many Bio Complete 3 should I take daily?

You should take two capsules of Bio Complete 3, twice a day before meals. For best results, Gundry MD recommends taking the product consistently to support gut health and digestion.

Should I take Bio Complete 3 with food?

For best results, you should take Bio Complete 3 before a meal.

Is Bio Complete 3 vegan?

This supplement does not claim to be vegan. Vegan readers of this Bio Complete 3 review should consult with a healthcare professional trained in nutrition before purchasing this product.

Is Bio Complete 3 gluten-free?

They made Bio Complete 3 with natural ingredients. Sunfiber is a gluten-free fiber, which acts as a prebiotic. The formula does not explicitly state that it is gluten-free.

What are the supplement facts of Bio Complete 3?

Each serving of 4 capsules of Bio Complete 3 contains:

  • Calories: 10
  • Total Fat: 1g
  • CoreBiome: 1,000mg
  • Sunfiber: 200mg
  • ProDura: 16mg

What is Gundry MD’s Shipping Policy?

Gundry MD can ‌ship out orders on the day you place your order. Issues due to COVID-19 have slightly reduced staff at the warehouse. US customers can expect to receive their order within 2-7 business days. International orders outside of the US should expect delays.

What is Gundry MD’s Return Policy?

Gundry MD is so confident that using their product will improve your gut health that they offer a 90-Day Money Back Guarantee.

If you are unhappy with your product experience for any reason, simply return the product for a full refund. Please note that the product must be purchased from the Gundry MD website to be eligible.

How to Contact Gundry MD

If you still have some questions after reading my Bio Complete 3 review, you can contact Gundry MD in a few ways:

  1. Phone: 800-852-0477
  2. Email: [emailprotected]
  3. Online Contact Form:

The customer service team at Gundry MD is available Monday to Friday between 6:00 am and 5:00 pm PST, and 6:00 am to 4:00 pm on the weekends.

Next, check out some similar reviews you might like:

UMZU Natural Supplements Review

Rae Wellness Supplements Review

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Article Sources

  1. Y. Mu, Y. Cong Bacillus coagulans and its applications in medicine Beneficial Microbes
Bio Complete 3 Review - Must Read This Before Buying (2024)


What is comparable to Bio Complete 3? ›

Core Nutritionals offers a comprehensive gut support product called Core GUT. Similar to Bio Complete 3, the company utilizes SunFiber as a prebiotic and CoreBiome (300mg tributyrin) as a postbiotic.

How long does it take for Bio Complete 3 to start working? ›

How Long Does It Take to See Results After Starting Bio Complete 3? Some users may begin to experience better digestion within a week. However, it usually takes at least a month to see results from Bio Complete 3. It may vary depending on factors such as metabolism and lifestyle.

What do people say about Bio Complete 3? ›

Not a very good trade off. I then tried antacids but any relief from them lasted for only 2-4 hours. Bio Complete 3 cured, let me say that again CURED!, my chronic indigestion, and restored normal bowel movements within three weeks. I now take it daily and have reliable daily bowel movements and no indigestion.

Is Bio Complete 3 FDA approved? ›

Bio Complete 3 Ingredients and Labeling

The main ingredients include Tributyrin, Sunfiber®, Bacillus coagulans, and flaxseed. These ingredients are generally recognized as safe (GRAS) by the FDA. Bio Complete 3's labeling adheres to FDA guidelines, providing clear dosage instructions and warnings.

Does Bio Complete 3 help with leaky gut? ›

While they both help with gut-related issues, Bio Complete 3 targets gut flora whereas Total Restore is designed to provide support for the gut lining. Both can help with IBS and Leaky Gut Syndrome.

What is the #1 substance to help heal the gut? ›

Glutamine. Glutamine is a non-essential amino acid that may have beneficial effects on the gut. A 2021 research review in Food Science and Human Wellness suggests glutamine might support the gut microbiome, modulate inflammatory responses and promote the integrity of the gut mucosal wall.

What plant protein does Dr Gundry recommend? ›

According to Dr. Gundry, the protein he recommends most is hemp. It is a complete protein, containing all the amino acids our body needs to function. Hemp protein powder is created by grinding hemp seeds into a powder and has a nutty taste, similar to flax.

What is the best gut supplement? ›

A quick look at the best probiotic supplements
  • Best overall : Culturelle Digestive Daily Probiotic Capsules | Skip to review.
  • Best for general gut health: Ritual Synbiotic+ | Skip to review.
  • Best for bloating: Mindbodygreen Probiotic+ | Skip to review.
  • Best subscription: Seed DS-01 Daily Synbiotic | Skip to review.

Does Bio Complete 3 contain butyrate? ›

About Gundry MD Bio Complete 3 Ingredients

CoreBiome™, the proprietary form of tributyrin used in Bio Complete 3, is designed to deliver butyrate directly to the gut, where it can exert its beneficial effects on digestive health.

What are the side effects of taking Bio Complete 3? ›

Now I know why. It has methyl cellulous [also used in eye drops] which causes bloating, microcrystalline [which causes gas, bloating, depression, forgetfulness, lack of energy, and headaches], and maltodextrin [which is a sugar substitute that has tons of articles debating whether it's safe or not].

What medications interact with probiotics? ›

Some medications that may interact with certain probiotics include: antibiotics, antifungals (such as clotrimazole, ketoconazole, griseofulvin, nystatin).

Does Bio Complete 3 expire? ›

I removed from my old bottle of Bio Complete 3 bottle the Printed label which reads 'DATE PRINTED IS MANUFACTURED DATE, NOT EXPIRATION DATE. PRODUCT IS GOOD FOR UP TO 2 YEARS FROM MGF DATE". This should be on all products.

What does Bio Complete 3 do for the body? ›

Digestive Health Support: With its unique blend, Bio Complete 3 may help nurture a healthy gut environment, encourage regular bowel movements, and assist digestion. Weight Management: As it helps regulate gut flora, it may help reduce cravings for junk food, which can be an ally in weight management efforts.

What is a gundry diet? ›

Gundry's program is based on the notion that lectin-loaded foods can harm your body and cause leaky gut. The theory is that eliminating these foods can help you lose weight, recover from chronic health conditions, reduce brain fog and more.

What are the side effects of bio sync? ›

Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems. A very serious allergic reaction to this drug is rare.

What foods does Dr Gundry say causes leaky gut? ›

Second, you may also want to cut lectin-containing foods from your diets. These include foods like oats, quinoa, brown rice, barley, rye, and whole wheat – along with nightshades like tomatoes, potatoes, and peppers. In general, you can begin to follow Dr. Gundry's YES and NO foods list to help reduce inflammation.

Which foods contain butyrate? ›

Butyrate is a major short-chain fatty acid produced during gut flora-mediated fermentation of dietary fibers. Legumes (beans, peas, and soybeans), fruits, nuts, cereals, and whole grains are good sources of dietary fibers. Butyrate is also found in butter and cheese.

Does magnesium heal a leaky gut? ›

Magnesium, like other minerals, has a cyclical relationship with leaky gut: not having enough can make inflammation happen faster, and more inflammation means you absorb less magnesium through your diet. 39 It also plays a secondary role by improving fatigue, a common leaky gut symptom.

What is the best supplement for repairing gut lining? ›


Glutamine is an important amino acid. In the digestive tract, it's best known for helping to repair the intestinal lining.

Do butyrate supplements really work? ›

Butyrate supplements have been shown to help improve symptoms of IBS and traveler's diarrhea, and to help improve bacterial balance in the gut microbiome. On the other hand, butyrate supplements have been shown not to help with ulcerative colitis and might trigger symptoms in people with certain gut problems.

What are the best digestive enzymes for leaky gut? ›

Certain enzymes like alpha-galactosidase, lactase and cellulase are often considered some of the best digestive enzymes for IBS as well as the best digestive enzymes for gas, bloating and stomach pain.


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